Publications 2016

  1. The haemodynamic hypothesis as a localising factor of vascular disease: a review
    Morbiducci U, Kok AM, Kwak BR, Stone PH, Steinman DA, Wentzel JJ (2016) Atherosclerosis at arterial bifurcations: evidence for the role of haemodynamics and geometry. Thrombosis and Haemostasis 115(3):484-92
  2. The relevance of aneurysm shape for disease understanding, categorization and decision making
    Hirsch S, Bijlenga P (2016) Shape? Shape. Shape!. Pan European Network: Science & Technology 18:178-181
  3. The relevance of aneurysm categorization and monitoring of shape in the clinical management
    Gondar R, Gautschi OP, Cuony J, Perren F, Jägersberg M, Corniola MV, Schatlo B, Molliqaj G, Morel S, Kulcsár Z, Mendes Pereira V, Rüfenacht D, Schaller K, Bijlenga P (2016) Unruptured intracranial aneurysm follow-up and treatment after morphological change is safe: observational study and systematic review. Journal of Neurology, Neurosurgery & Psychiatry 87:12 1277-1282

Publications 2017

  1. Incidental aneurysms are mostly stable and principal factors of instability are growth, changes in shape and vessel wall enhancement on MRI
    Wanke I, Bijlenga P, Rüfenacht D (2017) Zufallsbefund intrakranielles Aneurysma / Anévrisme intracrânien de découverte fortuite. Swiss Medical Forum Jan 2017
  2. Aneurysm location and size remain the principal factors to estimate aneurysm stability, risk of rupture and probability of treatment and adding other patient related factors leads to a marginal improvement
    Bijlenga P, Gondar R, Schilling S, Morel S, Hirsch S, Cuony J, Corniola M, Perren F, Rüfenacht D, Schaller K (2017) PHASES score for the management of intracranial aneurysm: a cross-sectional population based retrospective study. Stroke 48(8): 2105-2112
  3. Different hemodynamic environments may be responsible of different growth patterns. Global aneurysm growth was associated to increased wall shear stress and high wall shear stress gradient. Focal aneurysm growth was associated to low wall shear stress and focal high oscillatory shear index at the site of progression
    Machi P, Ouared R, Brina O, Bouillot P, Yilmaz H, Vargas MI, Gondar R, Bijlenga P, Lovblad KO, Kulcsár Z. (2017) Hemodynamics of focal versus global growth of small cerebral aneurysms. Clinical Neuroradiology, published online December 05 2017

Publications 2018

  1. Review on the role of  hemodynamic factors in the initiation and growth of intracranial aneurysms 
    Diagbouga MR, Morel S, Bijlenga P, Kwak BR. (2018) Role of hemodynamics in initiation/growth of intracranial aneurysms. Eur J Clin Invest. 2018 Sep;48(9):e12992. doi: 10.1111/eci.12992. Epub 2018 Jul 20. Review. PubMed PMID: 29962043
  2. The wall of aneurysm suspected to be at risk for rupture undergoes structural alterations relatively well associated with clinical and radiological factors currently used to predict this risk
    Morel S, Diagbouga MR, Dupuy N, Sutter E, Braunersreuther V, Pelli G, Corniola M, Gondar R, Jägersberg M, Isidor N, Schaller K, Bochaton-Piallat ML, Bijlenga P, Kwak BR (2018) Correlating Clinical Risk Factors and Histological Features in Ruptured and Unruptured Human Intracranial Aneurysms: The Swiss AneuX Study. J Neuropathol Exp Neurol. 2018 Jul 1;77(7):555-566. doi: 10.1093/jnen/nly031. PubMed PMID: 29688417; PubMed Central PMCID: PMC6005054.
  3. A case classifier using age, gender, shape and flow parameters allows to discriminate ruptured from unruptured intracranial aneurysms with an accuracy of 82%
    Detmer FJ, Fajardo-Jiménez D, Mut F, Juchler N, Hirsch S, Pereira VM, Bijlenga P, Cebral JR(2018) External validation of cerebral aneurysm rupture probability model with data from two patient cohorts. Acta Neurochir (Wien). 2018 Oct 30. doi: 10.1007/s00701-018-3712-8. Pubmed PMID:30374656

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